At a Glance
  • Denosyl contains a stabilized form of SAMe, which supports healthy liver function
  • The SAMe in Denosyl has been shown to be bioavailable
  • May support cognitive function in dogs
  • Nutramax Denosyl Liver and Brain Health Supplement, With S-Adenosylmethionine (SAMe)

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    About this product

    What is Denosyl?

    Denosyl is a daily supplement that helps support proper liver function. Support of a compromised liver, regardless of the cause, is essential if function is to be improved. Denosyl has not only been shown to markedly increase glutathione levels in the livers of dogs and cats, but to go far beyond that. Denosyl has been shown to protect liver cells from cell death and may be useful in cell repair and healing. Its main ingredient is S-Adenosylmethionine (SAMe). S-Adenosylmethionine, or SAMe, supports the liver by increasing levels of glutathione, a powerful antioxidant and the liver's main detoxifying agent.

    For:

    Cats and Dogs

    Benefits:

    • Denosyl contains a stabilized form of SAMe, which supports healthy liver function
    • The SAMe in Denosyl has been shown to be bioavailable
    • May support cognitive function in dogs

    How it Works:

    Denosyl has been shown to increase the level of glutathione, an antioxidant that can fight deadly toxins in your pet's body. For optimal absorption, it should be taken on an empty stomach.

    Cautions:

    Denosyl tablets must be given to your pet whole. Store this product in a cool and dry place. Keep tablets in the original blister pack until they are used.

    Brand Name:

    Denosyl (Nutramax)

    Active Ingredient(s):

    S-Adenosylmethionine

    What is this product used for:

    Denosyl has been shown to increase hepatic glutathione levels in cats and dogs. Glutathione is a potent antioxidant that protects liver cells from toxins and death. Denosyl is recommended to improve hepatic glutathione levels in compromised animals to help maintain and protect liver function.

    Availability:

    Denosyl is a non-prescription (OTC) product available as 90mg, 225mg and 425mg stabilized tablets.

    How this product should be used:

    The tablets should be given on an empty stomach at least one hour before feeding. Research shows that, if possible, a fasting period of 8-12 hours before giving this product is optimal. The usual dose in cats and dogs is based on weight. For pets up to 12 lbs give 1 tablet of the 90mg strength, for pets 13 to 34 lbs give 1 tablet of the 225mg strength, for pets 35 to 65 lbs give 1 tablet of the 425mg strength, for pets 66 to 120 lbs give 2 tablets of the 425mg strength and for pets over 120 lbs give 3 tablets of the 425mg strength. When giving more than 1 tablet the total number of tablets may be divided into morning and evening. For example, a dose of 3 tablets could be divided into 2 tablets in the morning and 1 tablet in the evening.

    What are the side effects:

    There are no reported side effects. However, Denosyl should be used with caution when given with medications such as amitriptyline, fluoxetine, clomipramine, tramadol, or Mitaban Dip.

    What special precautions are there:

    Tablets must be given whole. Do not break or split. Research shows that this product may be of benefit to pets that are also taking primidone, Phenobarbital, prednisone, azathioprine, cyclosporine and certain anti-depressants.

    In the event of overdose:

    Contact a veterinarian or veterinary emergency room.

    How should I store this product:

    Store this product in a cool, dry, place. Keep tablets in the original blister pack until used. Tablets are sensitive to moisture and extreme heat and should not be split or crumbled. Keep out of the reach of children.

    See more

    Denosyl Directions:

    • Tablets should be given on an empty stomach for optimal absorption.
    • They may be given at least two hours after a meal or one hour before a meal.
    Tip:

    The number of tablets administered may be gradually reduced, or increased, at any time at the recommendation of your veterinarian..

    Denosyl Dosage

    Denosyl for Small Dogs & Cats
    WeightDosage
    Up to 12 lbsGive 1 tablet daily
    Over 12 lbsGive 1 tablet twice daily
    Denosyl for Medium Dogs
    WeightDosage
    13-34 lbsGive 1 tablet daily
    Denosyl for Large Dogs
    WeightDosage
    35-65 lbsGive 1 tablet daily
    66-120 lbsGive 2 tablets daily
    121 lbs and overGive 3 tablets daily
    Denosyl Dosage for Horses:
    Horses
    Do not use!

    Denosyl Ingredients:

    Denosyl for Cats & Small Dogs
    Active Ingredients (up to 12 lbs)Amount
    S-Adenosylmethionine90 mg
    Denosyl for Medium Dogs
    Active Ingredients (13-34 lbs)Amount
    S-Adenosylmethionine225 mg
    Denosyl for Large Dogs
    Active Ingredients (35 lbs and over)Amount
    S-Adenosylmethionine425 mg
    Product Details
    plus minus

    What is Denosyl?

    Denosyl is a daily supplement that helps support proper liver function. Support of a compromised liver, regardless of the cause, is essential if function is to be improved. Denosyl has not only been shown to markedly increase glutathione levels in the livers of dogs and cats, but to go far beyond that. Denosyl has been shown to protect liver cells from cell death and may be useful in cell repair and healing. Its main ingredient is S-Adenosylmethionine (SAMe). S-Adenosylmethionine, or SAMe, supports the liver by increasing levels of glutathione, a powerful antioxidant and the liver's main detoxifying agent.

    For:

    Cats and Dogs

    Benefits:

    • Denosyl contains a stabilized form of SAMe, which supports healthy liver function
    • The SAMe in Denosyl has been shown to be bioavailable
    • May support cognitive function in dogs

    How it Works:

    Denosyl has been shown to increase the level of glutathione, an antioxidant that can fight deadly toxins in your pet's body. For optimal absorption, it should be taken on an empty stomach.

    Cautions:

    Denosyl tablets must be given to your pet whole. Store this product in a cool and dry place. Keep tablets in the original blister pack until they are used.

    Brand Name:

    Denosyl (Nutramax)

    Active Ingredient(s):

    S-Adenosylmethionine

    What is this product used for:

    Denosyl has been shown to increase hepatic glutathione levels in cats and dogs. Glutathione is a potent antioxidant that protects liver cells from toxins and death. Denosyl is recommended to improve hepatic glutathione levels in compromised animals to help maintain and protect liver function.

    Availability:

    Denosyl is a non-prescription (OTC) product available as 90mg, 225mg and 425mg stabilized tablets.

    How this product should be used:

    The tablets should be given on an empty stomach at least one hour before feeding. Research shows that, if possible, a fasting period of 8-12 hours before giving this product is optimal. The usual dose in cats and dogs is based on weight. For pets up to 12 lbs give 1 tablet of the 90mg strength, for pets 13 to 34 lbs give 1 tablet of the 225mg strength, for pets 35 to 65 lbs give 1 tablet of the 425mg strength, for pets 66 to 120 lbs give 2 tablets of the 425mg strength and for pets over 120 lbs give 3 tablets of the 425mg strength. When giving more than 1 tablet the total number of tablets may be divided into morning and evening. For example, a dose of 3 tablets could be divided into 2 tablets in the morning and 1 tablet in the evening.

    What are the side effects:

    There are no reported side effects. However, Denosyl should be used with caution when given with medications such as amitriptyline, fluoxetine, clomipramine, tramadol, or Mitaban Dip.

    What special precautions are there:

    Tablets must be given whole. Do not break or split. Research shows that this product may be of benefit to pets that are also taking primidone, Phenobarbital, prednisone, azathioprine, cyclosporine and certain anti-depressants.

    In the event of overdose:

    Contact a veterinarian or veterinary emergency room.

    How should I store this product:

    Store this product in a cool, dry, place. Keep tablets in the original blister pack until used. Tablets are sensitive to moisture and extreme heat and should not be split or crumbled. Keep out of the reach of children.

    See more
    How to use
    plus minus

    Denosyl Directions:

    • Tablets should be given on an empty stomach for optimal absorption.
    • They may be given at least two hours after a meal or one hour before a meal.
    Tip:

    The number of tablets administered may be gradually reduced, or increased, at any time at the recommendation of your veterinarian..

    Denosyl Dosage

    Denosyl for Small Dogs & Cats
    WeightDosage
    Up to 12 lbsGive 1 tablet daily
    Over 12 lbsGive 1 tablet twice daily
    Denosyl for Medium Dogs
    WeightDosage
    13-34 lbsGive 1 tablet daily
    Denosyl for Large Dogs
    WeightDosage
    35-65 lbsGive 1 tablet daily
    66-120 lbsGive 2 tablets daily
    121 lbs and overGive 3 tablets daily
    Denosyl Dosage for Horses:
    Horses
    Do not use!
    Ingredients
    plus minus

    Denosyl Ingredients:

    Denosyl for Cats & Small Dogs
    Active Ingredients (up to 12 lbs)Amount
    S-Adenosylmethionine90 mg
    Denosyl for Medium Dogs
    Active Ingredients (13-34 lbs)Amount
    S-Adenosylmethionine225 mg
    Denosyl for Large Dogs
    Active Ingredients (35 lbs and over)Amount
    S-Adenosylmethionine425 mg
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    $74.99
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